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apalutamide will reduce the level or impact of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Coadministration of apalutamide, a robust CYP3A4 inducer, with medicine that happen to be CYP3A4 substrates may lead to lower exposure to these medications.Will it make me so sleepy I are not able t